Quetiapine Treatment for Post-Traumatic Stress Disorder (PTSD)

Exclusion Criteria

• •History of sensitivity to quetiapine
• •Use of antipsychotics, antidepressants, or benzodiazepines (except for short-term use during study as specified in Concomitant Medications section) within one week prior to randomization and throughout the study period.
• •Medical conditions that may prevent safe administration of quetiapine including clinically significant hepatic, cardiac, or pulmonary disease.
• •Medical disorders that may cause or exacerbate anxiety symptoms.
• •Alcohol or drug abuse or dependence within one month of study entry as defined by DSM-IV criteria.
• •Schizophrenia, schizoaffective disorder, or bipolar disorder.
• •Suicidal or homicidal ideation or other clinically significant dangerousness
• •Currently seeking compensation or increase in compensation for the effects of the trauma.
• •Initiation or change in psychotherapy within 3 months of randomization.