A Study to Compare Cefdinir and Cephalexin for the Treatment of Mild to Moderate Uncomplicated Skin Infections

Exclusion Criteria

• •Medical history of hypersensitivity or allergic reaction to penicillin and/or cephalosporin (including cefdinir and cephalexin) antibiotics according to the judgment of the Investigator.
• •Subject with a complicated skin and skin structure infection as judged by the investigator.
• •A chronic or underlying skin condition at the site of infection (e.g., a secondary infected atopic dermatitis or eczema) or infections involving prosthetic materials (e.g., catheter tunnel infections, orthopedic hardware).
• •A wound secondary to burn injury or acne vulgaris.
• •Any infection site that requires:
• •* intraoperative surgical debridement;
• •* excision of infected lesions or body parts.
• •Infections that can be treated by surgical incision alone according to the judgment of the Investigator.
• •Any other infection that necessitates the use of additional concomitant oral or parenteral antibiotic therapy.
• •Known significant renal or hepatic impairment indicated by:
• •* Serum Creatinine \> 2.0 mg/dL (176.8 mol/L)
• •* SGOT (AST) \> 3x the upper limit of the reference range
• •* SGPT (ALT) \> 3x the upper limit of the reference range
• •* Alkaline Phosphatase \> 2x the upper limit of the reference range
• •* Total Bilirubin \> 2x the upper limit of the reference range
• •Underlying condition and/or disease that, according to the judgment of the Investigator, would be likely to interfere with completion of the course of study drug therapy or follow-up.
• •The Investigator considers the subject an unsuitable candidate for cefdinir or cephalexin administration