Cetuximab, Radiotherapy and Twice Weekly Gemcitabine to Treat Pancreatic Cancer

Exclusion Criteria

• •Acute hepatitis or known HIV
• •Active or uncontrolled infection
• •Significant history of cardiac disease
• •Prior therapy which affects or targets the EGF pathway
• •Prior severe infusion reaction to a monoclonal antibody
• •Any concurrent chemotherapy not indicated in the study protocol or any other investigational agents
• •Any previous chemotherapy or abdominal or pelvic radiotherapy
• •No prior malignancy is allowed except for adequately treated basal cell or squamous cell skin cancer, in situ cervical cancer, or malignancy for which the patient has been disease free for five years.
• •Any severe pre-existing medical or psychiatric condition, which, in the opinion of the attending physician, will interfere with safe and appropriate treatment and follow-up on study