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Cytokine Regulation of Periradicular Pain in Humans

NCT00223470·1 site·ClinicalTrials.gov

What this study is about

Take this into the appointment.

Saves the questions and what to expect into your notes, next to the visit they belong to.

Keep this study

Lead

The University of Texas Health Science Center at San Antonio

With

National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)

This study evaluates whether periradicular exudate concentrations of cytokines differ in patients experiencing pain and mechanical allodynia due to pulpal necrosis with an acute exacerbation of a chronic apical periodontitis, as compared to patients with pulpal necrosis with chronic apical periodontitis, but no pain or mechanical allodynia

Age

16–60

Sex

ALL

Healthy volunteers

Not accepted

You may be eligible if

1. Patient must be at least 16 years of age.
2. Clinical indication for Non-Surgical Root Canal Therapy (NSRCT).
3. 1st or 2nd maxillary or mandibular molar
4. Diagnosis must be Chronic Apical Periodontitis (CAP) with or without symptoms.
5. Intact, mature apices.
6. ASA I or II

You may not be if

1. Failure to meet any of the above
2. Previous NSRCT
3. Previous pulpotomy or pulpectomy
4. Suppurative apical periodontitis
5. Patients taking medications which can affect their pain rating or medications which effect their immune system ( such as glucocorticoids)

The record

StatusCompleted

PhaseNo phase

Taking part9

StartedOct 2002

UpdatedMar 9, 2012

Conditions

Chronic Apical Periodontitis of Pulpal Origin

Where1

Univerity of Texas Health Science Center at San Antonio
San Antonio, Texas, United States

Clareo Health | Cytokine Regulation of Periradicular Pain in Humans