A Study of Sertraline and Early Alprazolam XR Administration Versus Sertraline Only in Panic Disorder Patients

Exclusion Criteria

• •actively suicidal;
• •medical conditions for which either sertraline or alprazolam XR would be contraindicated;
• •recent six month history of substance or alcohol abuse;
• •history or presence of psychotic or bipolar disorder;
• •women who are pregnant or breastfeeding;
• •history or presence of a seizure disorder or a known history of more than one childhood febrile seizure;
• •presence of a personality disorder severe enough to compromise the investigator's ability to evaluate the efficacy and safety of the study medication;
• •concomitant therapy with other psychotropic medication(s);
• •clinically significant abnormality during physical examination, vital signs, EKG, urine drug screen, or laboratory tests at the screen visit.