Two-Dose Methotrexate for Ectopic Pregnancy

Inclusion Criteria

• •Confirmed diagnosis of ectopic pregnancy via
• •* D\&E without products of conception identified on frozen pathology or
• •* VABRA without products of conception identified with pathologic evaluation or
• •* Ultrasound visualization of a gestational sac in the adnexa, with definitive visualization of a yolk sac or fetal pole
• •the subject is hemodynamically stable without signs of hemoperitoneum
• •laparoscopy has not been performed
• •the subject is able to return for frequent follow-up care
• •normal renal and liver function have been documented within 2 days
• •normal white blood count and platelet count have been documented as per laboratory standard
• •normal chest x-ray was obtained if the subject has a history of pulmonary disease
• •no history of allergy or sensitivity to methotrexate or any component of its formulation