Trial to Investigate Immune Responses Elicited by a Liquid Formulation of Influenza Virus Vaccine (CAIV-T) in Healthy Children

Exclusion Criteria

• •whose parents or guardians are perceived to be unavailable or difficult to contact for evaluation or study visits during the study period;
• •with any serious chronic disease (e.g., with signs of cardiac or renal failure or severe malnutrition), including progressive neurological disease;
• •with Down's syndrome or other known cytogenetic disorders;
• •with a known or suspected disease of the immune system or those receiving immunosuppressive therapy, including systemic corticosteroids, or cytotoxic agents (see Section 4.2.2);
• •have an immunosuppressed or an immunocompromised individual living in the same household;
• •with a documented history of hypersensitivity to egg or egg protein or any other component of the study vaccine, placebo or TIV;
• •who, at anytime prior to study enrollment, receives any influenza vaccine (commercial or investigational);
• •with any medical conditions that in the opinion of the investigator might interfere with interpretation of the study results.
• •Note: A pregnant household member is not considered a contraindication to enrollment.