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Postoperative Pain After Medical Abortion Under Local Anesthesia : a Prospective and Randomized Trial Comparing Several Analgesic Regimen
* To compare postoperative analgesia by paracetamol 1gr or ketoprofen 100 mg or the combination of these two analgesics * each treatment beeing allocated by randomization
* 240 pregnant women who undewent a medical abortion by aspiration, under local anesthesia, (day case surgery) were enrolled after informed consent and signed approval * according to randomization, they received one hour before medical abortion procedure performed under local anesthesia of the cervix, one of these three diffrente analgesics : * paracetamol 1 gr * ketoprofen 100 mg * the association of both Postprocedure pain was recorded, by nurse, using a visual analog scale (VAS), 7 times before and after the procedure, until the discharge of the patient. * if VAS was above 40 on two consecutive measurements a morphine injection was given. * the number and total amount of morphine was recorded. * satisfaction was recorded within the 3 postoperative day by a telephone inquiry.
Age
18 - No limit years
Sex
FEMALE
Healthy Volunteers
No
Dept of Anesthesia - CHU
Angers, France
Start Date
September 1, 2002
Completion Date
August 1, 2003
Last Updated
November 1, 2017
240
Estimated participants
paracetamol
DRUG
ketoprofen
DRUG
ketoprofen + paracetamol
DRUG
Lead Sponsor
University Hospital, Angers
Data Source & Attribution
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