Accelerated Partial Breast Irradiation Following Lumpectomy for Breast Cancer

Exclusion Criteria

• •1. Men
• •2. Prior malignancy, breast or other if metastatic or with anticipated survival of \< 5 years
• •3. Pregnant women
• •4. Immunocompromised
• •5. Poorly controlled insulin dependent diabetes
• •6. Contraindication to radiotherapy, e.g. connective tissue disorder such as scleroderma
• •7. Breast cancer that involves skin or chest wall
• •8. Multifocal or Multicentric breast cancer
• •9. Invasive lobular carcinoma
• •10. Diffuse microcalcifications on mammography
• •11. Invasive carcinoma with extensive intraductal component (EIC)
• •12. Greater than 12 weeks since definitive surgical excision or completion of chemotherapy
• •13. Involved lymph nodes detected by frozen section or touch preparation at time of lumpectomy
• •14. Patients with 1 to 3 positive lymph nodes determined postoperatively (does not include patients with micro-metastases)
• •15. Subglandular or submuscular breast implants (does not include patients having implants placed AFTER intra-operative radiotherapy)