Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Vanderbilt University
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
On CHD dialysis for more than 6 months
Adequately dialyzed (Kt/V \> 1.0) with a biocompatible hemodialysis membrane. Patients with Kt/V \> 1.0 but \< 1.4 will be evaluated for etiologies of lower than optimal dialysis dose and every effort will be made to increase the Dialysis dose to 1.4 or above. Patients with all access types will be recruited to the study.
Suboptimal nutritional status identified by one of the following criteria:
1. Protein catabolic rate less than 1.0 g/kg/d calculated by three-point urea kinetic modeling on at least 2 occasions over the past 3 months
2. Progressive unintentional weight loss more than 2.5% of the initial or ideal body weight and/or patients who are less than 90% of ideal body weight.
3. Biochemical parameters of malnutrition defined by one of the following measurements over the consecutive two months prior to inclusion:
1. Serum albumin less than 4.0 g/dl
2. Serum transferrin concentration less than 250 mg/dl
3. Serum prealbumin concentration less than 32 mg/dl
4. Subjective Global Assessment Score less than 5.
You may not be if
Intolerance to nutritional supplementation (unable to tolerate any of the nutritional supplements available)
Refusal to sign a consent form
On nutritional supplementation (IDPN or PO) within 2 weeks of the study initiation.
