Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Michigan Rogel Cancer Center
With
Eli Lilly and Company
Barbara Ann Karmanos Cancer Institute
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
1. Patients must have histologic or cytologic diagnosis of pancreatic adenocarcinoma.
2. Patients must have clinical/radiologic evidence of metastatic disease (stage IV).
3. Patients must not have received prior chemotherapy for metastatic disease. Prior adjuvant chemotherapy is allowed, provided that the last day of therapy was at least 6 months prior to starting treatment.
4. Patients must have performance status of 0-2 on the SWOG scale.
5. Patients must have an estimated life expectancy of at least 12 weeks.
6. Patients must have adequate bone marrow function: absolute neutrophil count \>1,500/cmm, platelet count \>100,000/cmm.
7. Patients must be informed of the investigational nature of this study and must give written informed consent prior to the receiving of treatment per this protocol.
8. Patients must practice effective birth control while receiving treatment.
You may not be if
1. Patients with endocrine tumors or lymphoma of the pancreas.
2. Patients with locally advanced pancreatic cancer.
3. Patients with a proven history (radiographic and/or endoscopic) of peptic ulcer or esophageal erosions within one year of enrollment onto the study.
4. Patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other non-steroidal anti-inflammatory drugs.
5. History of active central nervous system (CNS) metastases.
6. Inadequate liver function (bilirubin \>3.0 mg/dL); transaminases (AST/ALT) \>3 times upper limit of institutional normal.
7. Inadequate renal function (creatinine \>1.5 mg/dL).
8. Serious concomitant systemic disorders incompatible with the study (at the discretion of the investigator).
9. History of other malignancy, except for cancers that have been treated with a curative intent and patient is without evidence of active disease.
10. Unresolved bacterial infection requiring treatment with antibiotics.
11. Pregnant or lactating women may not participate in the study.
12. Patients who have allergy to any of the study drugs or sulfa drugs.
13. Patients infected with HIV-1 virus because of the undetermined effect of this chemotherapy regimen in patients with HIV-1 and the potential for serious interaction with anti-HIV medications.
Clareo Health | Gemcitabine, Cisplatin, and Celecoxib Treatment of Metastatic Pancreatic Cancer
