Cellular Immune Responses to Hepatitis B Virus (HBV)- Longitudinal Follow up and Natural History

You may be eligible if

• There are two groups of patients in this study. Group A mono-infected with Hepatitis B, and those with co-infection HBV/HIV.
• Acute hepatitis B
• Chronic hepatitis B, HBV DNA+ve , normal ALT , HBeAg +ve
• Chronic hepatitis B, HBV DNA +ve , normal ALT, HBeAg -ve
• Chronic hepatitis , HBV DNA +ve, increased ALT, no HBV treatment B, HBeAg +ve
• Chronic hepatitis B, HBV DNA +ve , increased ALT, no HBV treatment B, HBeAg -ve
• Chronic hepatitis B, undergoing 'flare' of hepatitis
• To be HIV/HBV co-infected
• All patients:
• To be over 18 years