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Efficacy, Safety and Tolerability of Tegaserod in Patients With Chronic Constipation | Clinical Trials | Clareo Health

COMPLETEDPHASE4

Efficacy, Safety and Tolerability of Tegaserod in Patients With Chronic Constipation

NCT00149877•Novartis

Summary

Tegaserod (HTF919) is an aminoguanidine indole compound and a member of a new class of subgroup-selective 5-hydroxytryptamine (5-HT) agonists. The aim of this study is to investigate the efficacy, safety and tolerability of tegaserod on bowel habits in patients with CC.

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Male and females of at least 18 years of age
•A 12-month history of constipation (defined as \< three spontaneous bowel movements per week and ≥1 of the following symptoms \>25% of the time: hard stools, sensation of incomplete evacuation and straining)

Exclusion Criteria

•Patients with cancer, inflammatory bowel disease or other structural bowel disease
•Patients who participated in a prior tegaserod study
•Evidence of cathartic colon or laxative abuse, pelvic floor dysfunction or neurological disorders

Locations (1)

Novartis

Basel, Switzerland

Key Dates

Start Date

April 1, 2004

Completion Date

February 1, 2006

Last Updated

February 1, 2008

Enrollment

250

Estimated participants

Conditions

Chronic Constipation

Interventions

Tegaserod

DRUG

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: February 1, 2008Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Efficacy, Safety and Tolerability of Tegaserod in Patients With Chronic Constipation

Inclusion Criteria

Exclusion Criteria

Exploring the Potential Benefits of Probiotic Yogurt

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