Saves the questions and what to expect into your notes, next to the visit they belong to.
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Lead
University of Chicago
The purpose if this investigation is to evaluate the rate of improvement ub Quality of LIfe (QOL) in two different medications, a 10-day course of Cefdinir 300 mg PO BID versus a 10-day course of Amoxicillin/Clavulanate 1000 mg/62.5 mg XR BID, in the treatment of acute bacterial sinusitis.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Male and female outpatient adults greater than 18 years old fulfilling the case definition for acute bacterial sinusitis
Case definition includes clinical signs and symptoms, radiographic findings and collection of purulent material from the sinus
You may not be if
Symptoms less than 7 days and more than 3 weeks
History of sinus surgery within 3 months
History of frequent sinus infections (more than 2 episodes within the last 6 months)
History of kidney and liver disease
Pregnant and nursing women
Pre-existing disease that could predispose to sinus infections (cystic fibrosis or nasal polyps
Immunosuppressed patients
History of allergy to either drug. Patients with a documented history of allergies to either penicillin or cephalosporins will be excluded.
Clareo Health | Comparison Study Between Cefdinir & Amoxicilline/Clavulanate in Acute Sinusitis and Assessment of Quality of Life
