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The purpose is to examine the original breast tumor material to see how much of a metabolizing enzyme (CYP3A4) is present in tumor material. The researchers want to see if this is in any way associated with how the patient responded to docetaxel. They also want to examine the genes in the tumor that are responsible for the production of CYP metabolizing enzymes, to see if they are normal or if they have polymorphisms, or change compared to 'normal' CYP metabolizing enzymes.
Age
18 - No limit years
Sex
FEMALE
Healthy Volunteers
No
University of Michigan Cancer Center
Ann Arbor, Michigan, United States
Last Updated
March 26, 2008
Lead Sponsor
University of Michigan Rogel Cancer Center
NCT06625775
NCT06649331
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