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Effect of Pulse Width on Scar Treatment Using a 595-nm Pulsed Dye Laser | Clinical Trials | Clareo Health

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Effect of Pulse Width on Scar Treatment Using a 595-nm Pulsed Dye Laser

Effect of Pulse Width of a 595-nm Flashlamp-pumped Pulsed-dye Laser on the Treatment Response of Keloidal and Hypertrophic Sternotomy Scars

NCT00142441•Mahidol University

View on ClinicalTrials.gov

Summary

To investigate the effect of pulse width on the treatment response of keloidal and hypertrophic sternotomy scars to a 595-nm pulsed dye laser

Detailed Description

The pulse width of the previous model of pulsed dye laser was fixed at 0.45 millisecond, whereas the pulse widths of the latest model of PDL are tunable ranging between 0.45-40 milliseconds. The long-pulsed PDL has been proven to be safe and more effective in treating certain vascular abnormalities including adult port-wine-stain and small leg vein.9-12 In the present study, we would like to investigate the effect of pulse widths on the treatment response of keloidal and hypertrophic sternotomy scars to the 595-nm PDL.

Eligibility

Age

18 - 80 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Healthy, adult subjects aged above 18.
•Subjects must be in good health as determined by the investigator.
•Presence of keloidal and hypertrophic sternotomy scars for at least 6 months
•Subjects must have no prior treatment of the scar within 1 month before the first treatment session.
•Subject or authorized representative must sign Informed Consent Form prior to study enrollment.

Exclusion Criteria

•Female subjects known to be pregnant.
•Subjects with scleroderma, connective tissue disorders, hematologic disorders, hepatitis, infection, or uncontrolled diabetes mellitus.
•Subjects with photosensitive dermatoses such as Systemic Lupus Erythematosus (SLE)
•Subjects with a documented positive HIV test.
•Subjects who are on any types of anticoagulants.
•Subjects who are habitual smokers of cigars, pipe tobacco, or cigarettes.
•Subjects with history of radiation treatment at treatment sites.
•Subjects who use of any types of treatment of scars at the treatment site within one month before the first treatment visit.
•Subjects who are on medication that may interfere with wound healing or hemostasis.
•Subjects that have not signed the Informed Consent Form.

Locations (1)

Faculty of Medicine Siriraj Hospital

Bangkoknoi, Bangkok, Thailand

Key Dates

Start Date

June 1, 2003

Completion Date

December 1, 2004

Last Updated

June 3, 2016

Enrollment

Estimated participants

Conditions

KeloidsHypertrophic Scars

Interventions

Pulsed dye laser

DEVICE

Topical Cryotherapy and Keloid/Hypertrophic Scars

NCT07336368

Keloid ScarsHypertrophic Scars

View study

NOT_YET_RECRUITING

A Prospective Observational Clinical Study on Exploring the Value of Surgical Excision Combined With 32P Application in the Treatment of Keloids and the Factors Affecting the Prognosis of Combined Therapy

NCT07413497

KeloidsKeloids Scars

View study

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: June 3, 2016Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Effect of Pulse Width on Scar Treatment Using a 595-nm Pulsed Dye Laser

Inclusion Criteria

Exclusion Criteria

Topical Cryotherapy and Keloid/Hypertrophic Scars

A Prospective Observational Clinical Study on Exploring the Value of Surgical Excision Combined With 32P Application in the Treatment of Keloids and the Factors Affecting the Prognosis of Combined Therapy

Surgical Care And Recovery With Laser Evaluation Trial (SCARLET)

The Efficacy of Intralesional Bleomycin as Compared to 5-Flourouracil (5-FU) and Triamcinolone Acetonide (TAC) for the Treatment of Keloids: A Randomized Control Trial.

Observational Study of Keloids Scars Treated by Shaving and Cryosurgery