Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
GlaxoSmithKline
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Histologically or cytologically confirmed diagnosis of an advanced solid tumor malignancy that is not responsive to standard therapies or for which there is no standard therapy.
ECOG (Eastern Cooperative Oncology Group) Performance Status of 0-2.
You may not be if
Females who are pregnant or nursing.
Pre-existing hemolytic anemia.
Pre-existing peripheral neuropathy greater than or equal grade 2. Greater than or equal to 4 prior chemotherapy regimens including neoadjuvant/adjuvant chemotherapy, except breast cancer subjects who may have received more than 4 prior chemotherapy regimens.
Absolute neutrophil count less than 1,500/mm3.
Platelets less than 100,000/mm3.
Hemoglobin less than 9 g/dL.
Total bilirubin greater than1.5 mg/dL.
AST/ALT greater than 2.5 X upper limit of normal.
Creatinine clearance less than or equal to 50 mL/min (calculated by the Cockcroft Gault Formula).
Known contra-indications to the use of carboplatin, cisplatin, or other platinum-containing compounds.
