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Remission Keeping and Remission Inducing Effect by Vitamin-D in Crohns Disease, and in Vitro Vitamin-D Mediated T-Cell Immunomodulation
The purpose of this study is to examine whether vitamin D treatment is effective in Crohn's disease.
Crohns Disease is an inflammatory disease of primarily the small intestine and colon. In recent years scientists have hypothesized that low blood vitamin-D levels play a role in the development of autoimmune diseases, including Crohns disease. The purpose of this study is to examine whether vitamin-D is effective in keeping remission in inactive Crohns Disease (double blind placebo controlled trial). The patients who have active disease in the placebo group (reach primary endpoint), will in an open setting receive a higher single dose vitamin-D and the effect will be measured within 4 weeks.
Age
18 - 90 years
Sex
ALL
Healthy Volunteers
No
Aarhus University Hospital, Department V
Aarhus, Denmark
Hospital of Horsens
Horsens, Denmark
Hospital of Randers
Randers, Denmark
Hospital of Silkeborg
Silkeborg, Denmark
Start Date
September 1, 2005
Completion Date
February 1, 2008
Last Updated
April 13, 2007
110
Estimated participants
Vitamin D
DRUG
Lead Sponsor
University of Aarhus
Data Source & Attribution
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