Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Pennsylvania
With
Robert Wood Johnson Foundation
Age
18–any
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
Age\>18
A diagnosis for colon/rectal polyp resection, polypectomy
Subjects must be able to have the capacity and must be willing to provide informed consent
Premenopausal women must be surgically incapable of childbearing or be using a medically acceptable method of contraception (oral contraceptives, diaphragms, condoms with spermicide, IUD, progesterone injection or implant) throughout the entire length of the study
Men should wear condoms during the duration of the study given the unknown effects of curcumin on sperm viability, fertility
You may not be if
Previous or current history of colorectal cancer
Previous history of Familial Polyposis Syndromes
Previous history of inflammatory bowel disease
Previous surgery of the large bowel
Liver disease defined as AST and ALT\>3x upper limit of normal
Known history of gallstones, biliary colic or serum bilirubin \>2.0
Cardiac disease including myocardial infarction, congestive heart failure, arrhythmia
Renal disease defined as creatinine \>1.5
Hematopoietic disease defined as WBC\<4000, platelet count \<100,000, hemoglobin\<10.0 or coagulation or bleeding disorder
Significantly impaired gastrointestinal function or absorption
Peptic ulcer disease
Active infection including viral, bacterial, atypical or fungal infections of any organ system including HIV
Previous history of allergy to turmeric, Indian curries, aspirin or NSAIDs
Pregnant or lactating women
Dementia or other neurologic or psychiatric disease which may impede the ability to follow the protocol
Inability to swallow pills
Prior or concurrent therapy with any herbal or dietary supplement containing curcuminoids
Concurrent use of anticoagulants or antiplatelets including warfarin, clopidogrel
Prior or concurrent use of colorectal cancer chemopreventive agents including herbals: Sulindac or other NSAIDs, aspirin, COX-2 inhibitors, 5-aminosalicylate, folate, calcium, or their use within 14 days of enrollment
Concurrent use of immunosuppressants
Clareo Health | Curcumin for the Chemoprevention of Colorectal Cancer
