Picoplatin as Second-Line Therapy for Patients With Small Cell Lung Cancer

Exclusion Criteria

• •Prior radiotherapy that included \> 30% of the bone marrow (i.e., the whole of the pelvis or half of the spine).
• •Significant chronic or recent acute gastrointestinal disorder with diarrhea as a major symptom.
• •Significant heart disease.
• •Uncontrolled, untreated, unstable, or symptomatic brain tumors or central nervous system disease.
• •Grade 2+ peripheral neuropathy (a condition caused by damage to the nerves in the peripheral nervous system).