Escitalopram for the Treatment of Self-Injurious Skin Picking

Exclusion Criteria

• •Pregnant women or females of childbearing potential who do not consent to use of a medically acceptable method of contraception.
• •Women who are breastfeeding.
• •Subjects who pose a serious suicidal or homicidal risk in the judgment of study investigators.
• •Serious or unstable medical illness including cardiovascular, hepatic, renal, respiratory, endocrine, neurologic, or hematologic disease.
• •Subjects with a dermatologic disorder that causes pruritis.
• •Patients on anticoagulant therapy.
• •History of seizure disorder.
• •Comorbid bipolar disorder, psychosis, organic mental disorder, borderline personality disorder or developmental disorder. Subjects with obsessive compulsive disorder (with primary symptoms other than compulsive skin picking).
• •History of substance dependence. If there is a history of substance abuse, subjects should be in remission for ≥ 6 months.
• •Current treatment with cognitive behavioral therapy for skin picking.
• •Current use of another SSRI medication.
• •Other medications for medical disorders that might interfere with escitalopram.
• •Current major depression or prescribed an antidepressant for major depression within the past 12 months.
• •More than 1 adequate trial (at least 10 weeks at maximally tolerated dose) with another prior SSRI.