Omega-3 Fatty Acids in Preventing Breast Cancer in Women at High Risk of Developing Breast Cancer

Exclusion Criteria

• •PATIENT CHARACTERISTICS:
• •Age
• •18 and over
• •Sex
• •Female
• •Menopausal status
• •Not specified
• •Performance status
• •SWOG 0-1
• •Life expectancy
• •Not specified
• •Hematopoietic
• •Absolute granulocyte count ≥ 1,500/mm\^3
• •Platelet count ≥ 100,000/mm\^3
• •Hemoglobin ≥ 8.0 g/dL
• •Hepatic
• •SGOT and/or SGPT ≤ 2.5 times upper limit of normal (ULN)
• •Alkaline phosphatase ≤ 2.5 times ULN
• •Bilirubin ≤ 2.0 times ULN
• •Renal
• •Creatinine ≤ 2.0 mg/dL
• •Other
• •Not pregnant or nursing
• •Negative pregnancy test
• •No underlying medical, psychiatric, or social condition that would preclude study participation
• •No other invasive malignancy within the past 5 years except nonmelanoma skin cancer
• •PRIOR CONCURRENT THERAPY:
• •Biologic therapy
• •Not specified
• •Chemotherapy
• •Not specified
• •Endocrine therapy
• •More than 6 months since prior and no concurrent hormonal therapy, including any of the following:
• •* Antiestrogens
• •* Estrogen
• •* Selective estrogen-receptor modulators
• •* Progestins
• •* Aromatase inhibitors
• •* Hormonal contraceptives
• •Radiotherapy
• •Not specified
• •Surgery
• •No prior bilateral mastectomy
• •Other
• •More than 3 months since prior and no concurrent chronic (i.e., \> 3 times per week) non-steroidal anti-inflammatory drugs (e.g., aspirin, ibuprofen, or indomethacin) or cyclooxygenase-2 inhibitors
• •No prior cancer treatment that would preclude study treatment