Metastatic disease, with measurable lesions according to the Response Evaluation Criteria in Solid Tumors (RECIST);
Failure of prior cytokine therapy;
Documented progressive disease;
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Patients are ineligible for entry if any of the following criteria are met:
Significant cardiac disease including congestive heart failure, history of myocardial infarction within one year, uncontrolled dysrhythmias, or poorly controlled angina
History of serious ventricular arrhythmia
Corrected QT interval (QTc) ≥ 500 msec
Known infection with Human Immunodeficiency Virus (HIV), Hepatitis B, or Hepatitis C;
Previous extensive radiotherapy involving ≥ 30% of bone marrow
Coexistent second malignancy or history of prior malignancy within previous 5 years
Clareo Health | A Research Study for Patients With Metastatic Renal Cell Carcinoma