Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Abbott
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Males and females of at least 18 years of age with metastatic RCC of predominantly clear cell histology who have received 0 to 2 prior treatment regimens for metastatic disease.
Measurable disease according to Response Criteria for Solid Tumors.
Negative pregnancy test (women of childbearing potential only).
Pretreatment laboratory levels that meet specific criteria.
Signed and dated informed consent and authorization to use protected health information (in accordance with national and local patient privacy regulations
Patients must have failed at least one approved or investigational tyrosine kinase inhibitor (TKI).
You may not be if
Any of the following histologies of RCC: papillary, chromophobe, collecting duct, or unclassified.
Known sensitivity to murine proteins or chimeric antibodies or other components of the product.
Use of any investigational drug within 4 weeks prior to screening or 5 half-lives of the prior investigational drug (whichever is longer).
Systemic chemotherapy, immunotherapy, radiation therapy, or monoclonal antibody therapy within 4 weeks of M200 administration.
Documented central nervous system (CNS) tumor or CNS metastasis.
History of thromboembolic events and bleeding disorders within the past year.
Medical conditions that may be exacerbated by bleeding.
