S0344 Intralesional Resection in Treating Patients With Chondrosarcoma of the Bone

You may be eligible if

• DISEASE CHARACTERISTICS:
• Suspected low-grade intracompartmental chondrosarcoma, as defined by the following criteria:
• * Resorption of prior calcifications (indicated by a change in radiographic appearance over time) AND/OR meets at least 2, but no more than 4, of the following criteria:
• * Permeative appearance of medullary bone, defined as presence of tumor around 3 sides of a trabecula of normal bone
• * Endosteal scalloping, defined as \> 50% of adjacent cortical thickness
• * Cortical thickening beyond the thickness of adjacent normal bone
• * Bone expansion, defined as a circumferential increase in diameter of the bone beyond the adjacent normal bone
• * Positive (i.e., increased uptake or "hot") bone scan
• No cortical disruption and/or soft tissue mass by radiography and CT scan (3 mm cuts are optimal) or MRI
• No presumptive axial (spinal) involvement
• No multifocal disease by bone scan
• PATIENT CHARACTERISTICS:
• Age
• 18 and over
• Performance status
• Not specified
• Life expectancy
• Not specified
• Hematopoietic
• Not specified
• Hepatic
• Not specified
• Renal
• Not specified
• Other
• No other malignancy within the past 5 years except adequately treated basal cell or squamous cell skin cancer, carcinoma in situ of the cervix, or adequately treated stage I or II cancer in complete remission
• PRIOR CONCURRENT THERAPY:
• Biologic therapy
• No prior biologic therapy for this tumor
• Chemotherapy
• No prior chemotherapy for this tumor
• Endocrine therapy
• Not specified
• Radiotherapy
• No prior radiotherapy for this tumor
• Surgery
• No prior surgery for this tumor except biopsy\*
• No concurrent intramedullary fixation NOTE: \*Biopsy is not required
• Other
• No prior investigational anticancer agents for this tumor