The Effect of Ethanol on Brain Activity

Exclusion Criteria

• •1. have an abnormal physical exam and/or have laboratory values outside of normal ranges;
• •2. have fulfilled DSM-IV criteria for ethanol or other substance dependency (excluding nicotine) at any time;
• •3. have fulfilled DSM-IV criteria for a current or past major psychiatric disorder (DSM-IV Axis I) or who have ever had a head injury requiring hospitalization.
• •4. are over or under 20% of ideal body weight;
• •5. have taken any prescribed, non-prescribed, or over-the-counter medications or drugs within 14 days prior to the study days (excluding oral contraceptive agents);
• •6. are pregnant;
• •7. report to have a "facial flushing" response to the consumption of ethanol;
• •8. have never consumed at least two standard drinks of ethanol within one hour.
• •9. have ferromagnetic objects in their bodies, which might be adversely affected by MRI (e.g., surgical clips, metal fragments in or near brain, eye or blood vessels, cardiac or neurological pacemaker, cochlear or eye implant). Any doubt about presence of these objects will result in exclusion from this study.
• •10. Additionally, subjects will be asked to abstain from ethanol for at least 2 days prior to the studies.
• •11. Regular tobacco users will be excluded from the study in order to avoid nicotine withdrawal symptoms. Occasional (not daily) use of tobacco products is acceptable.
• •1. have an abnormal physical exam and/or have laboratory values outside of normal ranges;
• •2. have fulfilled DSM-IV criteria for any substance dependency (excluding alcohol or nicotine) at any time;
• •3. have fulfilled DSM-IV criteria for a current or past major psychiatric disorder or who have ever had a head injury requiring hospitalization.
• •4. are over or under 20% of ideal body weight;
• •5. have taken any prescribed, non-prescribed, or over-the-counter medications or drugs within 14 days prior to the study days (excluding oral contraceptive agents);
• •6. are pregnant;
• •7. report to have a "facial flushing" response to the consumption of ethanol;
• •8. have never consumed at least two standard drinks of ethanol within one hour.
• •9. have ferromagnetic objects in their bodies, which might be adversely affected by MRI (e.g., surgical clips, metal fragments in or near brain, eye or blood vessels, cardiac or neurological pacemaker, cochlear or eye implant). Any doubt about presence of these objects will result in exclusion from this study.
• •10. Additionally, subjects will be asked to abstain from ethanol for at least 2 days prior to the studies.
• •11. Regular tobacco users will be excluded from the study in order to avoid nicotine withdrawal symptoms. Occasional (not daily) use of tobacco products is acceptable.