Treatment of Rheumatoid Arthritis With Marine and Botanical Oils

Inclusion Criteria

• •Definite RA with onset at \> 16 years, with total disease duration of at least 6 months
• •Active disease as manifested by at least 3 joints that are swollen and 6 joints that are tender at time of enrollment, and either an erythrocyte sedimentation rate \>\_28, or a CRP \>1.4, or morning stiffness of at least 45 min
• •Stable dose of DMARDs for 2 mos before baseline visit, with total duration of DMARD for 6 mos.
• •All standard therapy for RA, including DMARDs and combinations of DMARDs will be allowed as long as doses have been stable for 2 mos
• •Stable NSAID for 1 month before baseline if on an NSAID
• •Stable prednisone dose of \< 10 mg/day for 1 month before baseline visit, if on prednisone
• •Ability to give and understand all elements of informed consent
• •Absence of comorbid condition which, in the opinion of the physician-investigator, would render the patient unsuitable for the study
• •Willingness to adhere to the clinical protocol.