Use of Black Cohosh and Red Clover for the Relief of Menopausal Symptoms

Exclusion Criteria

• •Contraindications for hormone replacement therapy
• •Diabetes mellitus
• •Pregnancy or breast-feeding
• •Obese (BMI \>35 excluded)
• •History of endometrial hyperplasia/neoplasia/malignancy
• •History of breast or reproductive cancer
• •History of severe recurrent depression, or severe psychiatric disturbance
• •History of stroke/CVA, severe varicose veins, sickle cell anemia, myocardial infarction (heart attack), or arrhythmia (rhythm disturbance of the heart)
• •History of abnormal vaginal bleeding of unknown cause
• •Untreated or uncontrolled high blood pressure/hypertension
• •Use of any medication or supplement containing estrogen, progestin, SERM, St. John's Wort, bisphosphonates, or phytoestrogens
• •History of hormone-associated migraines
• •History of deep vein thrombosis (blood clots), thrombophlebitis, or thromboembolic disorders
• •Participation in a clinical trial within 30 days
• •Abnormal endometrial biopsy or mammogram
• •Abnormal transvaginal ultrasound defined as \>7mm thickness
• •Vegan