Radiation Therapy and the Natural History of Childhood Cancers

BACKGROUND -Children with cancer represent relatively rare disorders that are of unique scientific importance and educational value. OBJECTIVE -This protocol will allow follow-up of these patients for determination of the effects of radiation on overall survival, as well as relapse-free/ disease-free survival, local control, and the late sequelae of radiation therapy. ELIGIBILITY -Children with cancer and who require radiation are referred to the Radiation Oncology Branch primarily from Children's National Medical Center in Washington, D.C. and from other Branches of the NCI/NIH. DESIGN -This protocol is designed to provide the radiation component of therapy in children with cancer that have diseases that are of unique scientific interests, importance, and/or educational value.