Safety and Efficacy of Study Drug Versus Placebo for Negative Symptoms of Schizophrenia

You may be eligible if

• Inclusion:
• Adults aged 18-60
• Current diagnosis of schizophrenia
• Significant negative symptoms with few positive symptoms (e.g. hallucinations, delusions) and no evidence of major depression.
• Female subjects of childbearing potential must test negative for pregnancy at the time of enrollment.
• Subjects must be able to provide consent
• Must be healthy based on medical exam, laboratory tests and electrocardiogram
• Exclusion:
• Female subjects who are either pregnant or nursing.
• Acute or unstable medical conditions
• Diseases of the central nervous system
• Subjects who are judged clinically to be at serious risk for suicide or violence
• Subjects with delusional disorder, psychotic disorder NOS, schizophreniform, schizoaffective disorder, bipolar disorder, attention deficit/hyperactivity disorder, major depressive disorder,alcohol or drug dependence