Genetic Study of Familial Factors in Patients With Colon Cancer

You may be eligible if

• DISEASE CHARACTERISTICS:
• Diagnosis of colon cancer or polyps at age 70 or under
• Has a living full sibling with diagnosis of colon cancer or polyps at age 70 or under
• No history of familial adenomatous polyposis syndrome
• No hereditary nonpolyposis colon cancer, according to Amsterdam criteria
• No known I1370K adenomatous polyposis of the colon susceptibility variant
• Enrolled on 1 of the following clinical trials:
• * CLB-9581
• * CLB-89803
• * CLB-80001 NOTE: Patients do not need to be receiving protocol therapy. Patients who are outside the treatment protocol's follow-up range are eligible. Patients who discontinued therapy for any reason, including toxic effects, are eligible.
• PATIENT CHARACTERISTICS:
• Age
• 70 and under at diagnosis
• Other
• No significant psychiatric illness that would preclude giving informed consent
• No inflammatory bowel disease (in patient or sibling)