Study of the Safety and Efficacy of SU-011,248 in Adult Patients With Advanced Kidney Cancer

Exclusion Criteria

• •Prior treatment with any systemic therapy other than 1 prior cytokine-based treatment regimen;
• •Prior surgical resection of or irradiation to the only site of measurable disease;
• •Ongoing severe hematuria;
• •Other active second malignancy;
• •Cardiovascular diseases or conditions within the last 12 months;
• •Known brain metastases;
• •Known HIV-positive or AIDS-related illness;
• •Pregnant or breast-feeding women;
• •Current participation in other clinical trials;
• •Other severe acute or chronic medical conditions.