Seizures caused by metabolic disturbance, toxic exposure, or active infection

A primary diagnosis of generalized epilepsy (exception - secondarily generalized seizures)

A history of status epilepticus within 30 days

Seizures not related to epilepsy

Frequent use of additional anti-epileptic medications to treat increases in seizures (for example: rectal diazepam)

Taking felbamate within 6 months

Serum sodium levels \<135 mEq/L

Significant heart, breathing, kidney, stomach, liver, blood, or cancer disorder requiring treatment/therapy

A history of chronic infection (e.g., hepatitis or HIV)

Significant electrocardiogram (ECG) abnormalities

A nursing mother taking anti-convulsant drugs

Previously demonstrated sensitivity/allergic reaction to Trileptal or related compounds

Used experimental medication within 30 days of entering this study

Pediatric Epilepsy Study