Isoflavones & Lycopene in Localized Prostate Ca:Prior to Radical Prostatectomy

You may be eligible if

• DISEASE CHARACTERISTICS:
• Histologically confirmed localized prostate cancer
• * Stage I or II
• Scheduled prostatectomy between 4-6 weeks after initial biopsy
• PATIENT CHARACTERISTICS:
• Age:
• 45 to 80
• Performance status:
• Not specified
• Life expectancy:
• Not specified
• Hematopoietic:
• Not specified
• Hepatic:
• No known history of hepatic disease
• Renal:
• No known history of renal disease
• Other:
• No known history of thyroid disease
• Body mass index no greater than 32
• Omnivorous diet
• No known allergy to study supplements
• No evidence of prostatitis or urinary tract infection
• No other prior malignancy except nonmelanoma skin cancer
• Fertile patients must use effective contraception
• PRIOR CONCURRENT THERAPY:
• Biologic therapy:
• Not specified
• Chemotherapy:
• Not specified
• Endocrine therapy:
• No concurrent thyroid hormone replacement medications
• Radiotherapy:
• Not specified
• Surgery:
• See Disease Characteristics
• Other:
• At least 30 days since prior antibiotics
• At least 30 days since prior diet high in soy and/or lycopene products (e.g., greater than 40 mg soy/day and/or greater than 15 mg lycopene/day)
• No other concurrent nutritional supplements, including modular supplements with other carotenoids and isoflavones
• No prior or concurrent therapy for prostate cancer