Positron Emission Tomography Before Surgery in Evaluating Women With Primary or Recurrent Breast Cancer

Inclusion Criteria

• •DISEASE CHARACTERISTICS:
• •Diagnosis of breast cancer for which surgical intervention is planned
• •* Large primary breast cancer (i.e., larger than 5 cm, T3) as determined by prior biopsy, physical exam, or mammogram OR
• •* Locally advanced breast cancer (T4) OR
• •* Clinical suspicion of axillary nodal disease (N1-2) (i.e., stage IIB-IIIA) OR
• •* Locally or regionally recurrent disease
• •No locally recurrent disease that is non-invasive (i.e., ductal carcinoma in situ)
• •No locally advanced disease (e.g., inflammatory breast cancer) that will be treated with neoadjuvant chemotherapy without surgery
• •Hormone receptor status:
• •* Not specified
• •PATIENT CHARACTERISTICS:
• •Age:
• •Not specified
• •Sex:
• •Female
• •Menopausal status:
• •Not specified
• •Performance status:
• •Not specified
• •Life expectancy:
• •Not specified
• •Hematopoietic:
• •Not specified
• •Hepatic:
• •Not specified
• •Renal:
• •Not specified
• •Other:
• •No other malignancy except previously treated nonmelanoma skin cancer or carcinoma in situ of the cervix
• •No known active infection
• •No autoimmune disease or inflammatory disease (e.g., sarcoidosis or rheumatoid arthritis)
• •Able to fast for 6 hours and tolerate a FDG-PET scan for the duration of the test
• •Not pregnant or nursing
• •PRIOR CONCURRENT THERAPY:
• •Biologic therapy:
• •Not specified
• •Chemotherapy:
• •See Disease Characteristics
• •Endocrine therapy:
• •Not specified
• •Radiotherapy:
• •Not specified
• •Surgery:
• •See Disease Characteristics