EEG and EMG Studies of Hand Dystonia

Exclusion Criteria

• •Healthy subjects: abnormal neurological exam or history of past neurological disease.
• •Dystonia patients: the presence of a second neurological disease or condition; abnormal neurological findings on exam that are not related to their focal hand dystonia.
• •For MRI studies, patients with metallic implants will be excluded to remove potential risks from this procedure.
• •For MRI purposes, women who are pregnant are excluded from this part of the protocol. Therefore, all women of childbearing potential will have a pregnancy test performed prior to prospective MRI studies, which must be negative, before proceeding.
• •For TMS studies, healthy volunteers or focal hand dystonia patients who have a pacemaker, an implanted medical pump, a metal plate or metal object in the skull or eye (for example, after brain surgery), or who have a history of seizure disorder will be excluded from the trial.