Finding studies
Finding studies
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Lead
Centers for Disease Control and Prevention
With
Primary Objective: To evaluate the efficacy of a directly-observed, largely-intermittent, six-month regimen of rifampin, pyrazinamide, ethambutol among patients with culture confirmed isoniazid-resistant M. tuberculosis. Secondary Objectives: To describe the rate, severity and timing of toxicities and drug intolerances associated with this treatment regimen. To describe the utility of this regimen among patients who are unable to continue the standard 4-drug regimen due to the development of intolerance to isoniazid
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted