Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Centers for Disease Control and Prevention
With
US Department of Veterans Affairs
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Clinical diagnosis of pulmonary \&/or extrapulmonary TB confirmed by a positive culture and susceptibility to rifampin. Patients having isoniazid or pyrazinamide (PZA)-resistant isolates are eligible to continue in the study on a modified regimen
Evidence of HIV infection confirmed by a positive serologic test (ELISA and Western Blot).
Absolute neutrophil count \>500/mm3 (use of colony stimulating factors, filgrastim, or sargramostim is allowed)
\> 18 years of age
Willingness to practice effective contraception if applicable
Signed informed consent
You may not be if
Pregnancy or breastfeeding
AST \> 10 times the upper limit of normal
Bilirubin \> 3.0 times the upper limit of normal
Creatinine \> 3.0 times the upper limit of normal
Intolerance to any of the study drugs except isoniazid or pyrazinamide
Concomitant disorder that is contraindication to the use of the study drugs
More than 28 days of treatment for active tuberculosis within the 6 months prior to this course of therapy
Bone/joint tuberculosis or silicotuberculosis
Clareo Health | TBTC Study 23: Treatment of HIV-Related Tuberculosis Using a Rifabutin-Based Regimen
