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COMPLETEDPhase 3NCT00021814

Medical Therapy of Prostatic Symptoms

The Medical Therapy of Prostatic Symptoms (MTOPS) is a clinical research study sponsored by the National Institutes of Health (NIH). The study will test whether the oral drugs finasteride (Proscar) an...

Lead sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)•17 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Collaborators

George Washington University

Age

50 - No limit years

Sex

MALE

Healthy Volunteers

Yes

Inclusion Criteria

•Peak urinary flow rate at least 4 ml/sec but not greater than 15 ml/sec; and voided volume is at least 125 ml.
•American Urological Association Symptom Score is greater than or equal to 8 and less than or equal to 30.
•Voluntarily signed the informed consent agreement prior to the performance of any study procedures.

Exclusion Criteria

•Serum prostate specific antigen level greater than 10 ng/ml.
•Supine blood pressure less than 90/70 mmHG. Orthostatic hypotension.
•Any prior medical or surgical intervention for BPH.
•Received any prior experimental intervention (either medical or surgical) for prostate disease or enrolled in any other study protocol.

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: September 28, 2018Terms

Trial snapshot

StatusCOMPLETED

PhasePHASE3

Enrollment3,407

Start dateDec 1995

Last updatedSep 28, 2018

Condition

Prostatic Hyperplasia Prostatic Hypertrophy, Benign

Locations shown

University of California

La Jolla, California

Univ of Colorado Health Sciences Center

Aurora, Colorado

Yale University

New Haven, Connecticut

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: September 28, 2018Data synced to Clareo: May 3, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions