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Genetic Analysis of Familial Brain Aneurysms | Clinical Trials | Clareo Health

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COMPLETEDNCT00011856

Genetic Analysis of Familial Brain Aneurysms

This study will investigate cerebral (brain) aneurysms and their possible inheritance patterns in families. It will try to determine how often brain aneurysms occur in families in which more than one ...

Lead sponsor: National Human Genome Research Institute (NHGRI)•1 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

National Human Genome Research Institute (NHGRI)

This study is designed to explore the genetics of familial cerebral aneurysms. Families in which more than one person has had a known cerebral aneurysm will be studied. Family histories will be obtained and participants identified who are willing to come to the NIH Clinical Center for an MRAngiograph and venipuncture. DNA will be isolated and linkage studies undertaken to identify loci involved in the etiology of familial cerebral aneurysms, using standard linkage approaches.

Age

All ages

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Participants and their relatives that are affected or at a higher risk for cerebral aneurysms will be enrolled in this protocol.

Exclusion Criteria

•For the MR Angiograph portion of the study, any participant that is not able to sign the Clinical Center consent form due to metal implants, pregnancy, claustrophobia, or an allergy to gadolinium as a contrast will be excluded from the imaging part of the study.

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: March 4, 2008Terms

Trial snapshot

StatusCOMPLETED

Phase—

Enrollment300

Start dateFeb 2001

Last updatedMar 4, 2008

Condition

Intracranial Aneurysm

Locations shown

National Human Genome Research Institute (NHGRI)

Bethesda, Maryland

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: March 4, 2008Data synced to Clareo: July 13, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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