North American Study for the Treatment of Refractory Ascites (NASTRA)

Inclusion Criteria

• •Cirrhosis as documented by biopsy or clinical/laboratory parameters WITH
• •Tense symptomatic ascites and need for paracentesis (10 L) within last 2 months AND
• •Failure of medical therapy as defined by the inability to lose at least 3.3 lbs/week while on maximum doses of diuretics or diuretic related complications (severe hyponatremia, hypercalcemia, azotemia or encephalopathy)