Pilot Study of Enalapril and Renal Function in Patients With IgA Nephropathy

Inclusion Criteria

• •Histologically confirmed IgA nephropathy, diagnosed within the past 3 years
• •Clinical presentation of either isolated hematuria/proteinuria for less than 3 years OR
• •Acute nephritic or nephrotic syndrome
• •No secondary forms of IgA nephropathy associated with chronic inflammatory disease of the bowel and liver
• •No end stage renal failure as defined by the following: Glomerular filtration rate less than 15 mL/min AND Extensive glomerulosclerosis and tubulointerstitial damage
• •No systemic lupus erythematosus or systemic (extrarenal) vasculitis (Henoch-Schonlein syndrome)
• •Healthy volunteers will be accrued as a control group
• •No other concurrent medical or psychiatric illness that would preclude study