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COMPLETEDNCT00004306

Clinical and Molecular Correlations in Spinocerebellar Ataxia Type 10 (SCA10)

OBJECTIVES: I. Clinically evaluate members from families with a dominantly inherited ataxia and collect blood, skin and muscle samples for detailed molecular studies. II. Perform detailed clinical ev...

Lead sponsor: Office of Rare Diseases (ORD)•1 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Office of Rare Diseases (ORD)

Collaborators

The University of Texas Medical Branch, Galveston

PROTOCOL OUTLINE: Participants undergo a comprehensive clinical and molecular evaluation. Studies include: neurologic evaluation, including magnetic resonance imaging and nerve conduction studies; ophthalmologic exam; audiologic exam, including auditory brain stem evoked response; DNA extraction from blood, skin and muscle; genotype phenotype correlation. A neuropathologic evaluation is conducted postmortem, when possible.

Age

3 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Subjects who have the diagnosis of SCA10 and their immediate relatives.

Exclusion Criteria

•Children under 3 years of age, pregnant women, prisoners, mentally incapacitated subjects, and subjects who do not give consent.

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: March 6, 2012Terms

Trial snapshot

StatusCOMPLETED

Phase—

Enrollment18

Start dateNov 1999

Last updatedMar 6, 2012

Condition

Hereditary Ataxia

Locations shown

University of Texas Medical Branch at Galveston

Galveston, Texas

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: March 6, 2012Data synced to Clareo: June 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions