A Study of Retrovir and Epivir Alone or in Combination With 141W94 in HIV-Infected Patients

Exclusion Criteria

• •Co-existing Condition:
• •Patients with the following symptoms or conditions are excluded:
• •Clinical diagnosis of AIDS (CDC 1993 Classification C).
• •Concurrent Medication:
• •Excluded:
• •Terfenadine, astemizole, cisapride, triazolam, medazolam, and ergotamine/dihydroergotamine-containing regimens.
• •Patients with the following prior conditions are excluded:
• •Clinically relevant hepatitis in the previous 6 months.
• •Prior Medication:
• •Excluded:
• •Greater than 4 weeks of any nucleoside antiretroviral therapy.
• •Previous therapy with an HIV protease inhibitor.
• •Cytotoxic chemotherapeutic agents within 4 weeks prior to entry.
• •Immunomodulating agents within 3 months prior to entry.
• •Prior Treatment:
• •Excluded:
• •Radiotherapy within 4 weeks prior to entry.
• •Risk Behavior:
• •Excluded:
• •Current alcohol or illicit drug use that may interfere with the patient's ability to comply with the dosing schedule or protocol evaluations.