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Azithromycin in the Treatment of Cryptosporidiosis in Patients With Acquired Immune Deficiency Syndrome (AIDS): A Randomized, Multi-Center, Placebo-Controlled, Double-Blind Study | Clinical Trials | Clareo Health

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Azithromycin in the Treatment of Cryptosporidiosis in Patients With Acquired Immune Deficiency Syndrome (AIDS): A Randomized, Multi-Center, Placebo-Controlled, Double-Blind Study

NCT00002082•Pfizer

View on ClinicalTrials.gov

Summary

To evaluate the safety and efficacy of azithromycin in the treatment of intestinal cryptosporidial infection in AIDS patients.

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Concurrent Medication:
•Allowed:
•Zidovudine.
•Antidiarrheal medication with imodium or paregoric only.
•Patients must have:
•HIV infection.
•Intestinal cryptosporidiosis proven by stool microscopy on at least two occasions prior to study enrollment.
•Life expectancy of at least 2 weeks by clinical assessment. In states where the legal age of consent for medical procedures is 21 years, patients below the age of 21 must have consent of parent or guardian.
•Prior Medication:
•Allowed:
+1 more criteria

Exclusion Criteria

•Co-existing Condition:
•Patients with the following symptoms and conditions are excluded:
•Known hypersensitivity or significant intolerance to macrolide antibiotics.
•Marked abnormalities of liver or renal function.
•Causes for diarrhea other than, or in addition to, cryptosporidiosis.
•Inability to receive oral medication.
•Concurrent Medication:
•Excluded:
•Cancer chemotherapy (including therapy for Kaposi's sarcoma).
•Any drug or biologic preparation (e.g., bovine colostrum, paromomycin, spiramycin, somatostatin) with possible anticryptosporidial activity.
+7 more criteria

Locations (4)

Infectious Disease Med Group

Oakland, California, United States

UCSD Med Ctr

San Diego, California, United States

Cornell Univ Med Ctr

New York, New York, United States

Univ of Tennessee

Memphis, Tennessee, United States

Key Dates

Last Updated

June 24, 2005

Conditions

CryptosporidiosisHIV Infections

Interventions

Azithromycin

DRUG

Skeletal Muscle Energetics and Fatiguability in Older Individuals

NCT04142047

HIVHIV Infections

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RECRUITINGPHASE3

A Study to Evaluate the Effectiveness of Long-acting (LA) Cabotegravir (CAB) + Rilpivirine (RPV) LA When Given to Participants With Detectable HIV-1

NCT06694805

HIV Infections

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RECRUITING

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: June 24, 2005Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Azithromycin in the Treatment of Cryptosporidiosis in Patients With Acquired Immune Deficiency Syndrome (AIDS): A Randomized, Multi-Center, Placebo-Controlled, Double-Blind Study

Inclusion Criteria

Exclusion Criteria

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