Evaluation and Long-Term Follow-up of Patients With Inflammatory Disorders

You may be eligible if

• INCLUSION CRITIERIA:
• Males and females ages 2 years and older.
• Inflammatory conditions associated with, but not limited, to acute and chronic infections or presumed infections, and congenital or acquired immunologic disorders, as determined by the principal or associated investigators.
• A NIAID/LCIM investigator has an interest in the patient's illness and is willing to serve as attending physician to supervise the patient's medical care at the NIH.
• If appropriate, immediate family members of patients with inflammatory conditions may be evaluated under this protocol to determine if they may also be affected by their relative's disease.
• Willingness to participate in clinical protocols when appropriate.
• Subjects must maintain a primary physician outside NIH for non-protocol related medical complaints and for emergency medical treatment required for these or other of their disorders.
• Willingness to have samples stored and to provide tissue samples for studying immune dysregulation and for genetic analysis.
• Ablility to provide informed consent or, for the patient cohort, has a designated legally authorized representative (LAR).
• For females, not pregnant.