Evaluation and Long-Term Follow-up of Patients With Inflammatory Disorders

Inclusion Criteria

• •INCLUSION CRITIERIA:
• •Males and females ages 2 years and older.
• •Inflammatory conditions associated with, but not limited, to acute and chronic infections or presumed infections, and congenital or acquired immunologic disorders, as determined by the principal or associated investigators.
• •A NIAID/LCIM investigator has an interest in the patient s illness and is willing to serve as attending physician to supervise the patient's medical care at the NIH.
• •If appropriate, immediate family members of patients with inflammatory conditions may be evaluated under this protocol to determine if they may also be affected by their relative s disease.
• •Willingness to participate in clinical protocols when appropriate.
• •Subjects must maintain a primary physician outside NIH for non-protocol related medical complaints and for emergency medical treatment required for these or other of their disorders.
• •Willingness to have samples stored and to provide tissue samples for studying immune dysregulation and for genetic analysis.
• •Ablility to provide informed consent or, for the patient cohort, has a designated legally authorized representative (LAR).
• •For females, not pregnant.