The Effectiveness of Three Anti-HIV Drug Combinations in HIV-Infected Patients Who Have Never Used Anti-HIV Drugs

Exclusion Criteria

• •Co-existing Condition:
• •Patients with the following symptoms or conditions are excluded:
• •Serious underlying medical condition other than HIV such that life expectancy is less than 2 years.
• •Malignancy requiring systemic cytotoxic chemotherapy.
• •Active grade 2 or worse peripheral neuropathy.
• •Concurrent Medication:
• •Excluded:
• •Antiretrovirals other than study drugs.
• •Systemic cytotoxic chemotherapy.
• •Foscarnet.
• •Patients with the following prior conditions are excluded:
• •Chronic diarrhea defined as three or more stools per day for 15 days, within 30 days prior to study entry.
• •Unexplained temperature \>= 38.5 C for any 7 days within 30 days prior to study entry.
• •Active participation in other experimental therapy within 30 days prior to study entry.
• •Prior Medication:
• •Excluded:
• •Prior nucleoside antiretrovirals of 1 week or longer duration.
• •Any antiretroviral within 90 days prior to study entry.
• •Non-nucleoside reverse transcriptase inhibitors and protease inhibitors within 30 days prior to study entry.
• •Biologic response modifiers such as IL-2 and interferon within 30 days prior to study entry.