The Effectiveness of Two Anti-HIV Treatments in HIV-Infected Patients

Exclusion Criteria

• •Co-existing Condition:
• •Patients with the following symptoms or conditions are excluded:
• •Presence of factors predisposing to pancreatitis such as active alcoholism.
• •Other medical conditions that would interfere with study compliance.
• •Concurrent Medication:
• •Excluded:
• •Other antiretrovirals or systemic immunomodulators.
• •Systemic corticosteroids.
• •Systemic cytotoxic chemotherapy.
• •Intravenous pentamidine.
• •Concurrent Treatment:
• •Excluded:
• •Radiation therapy except to local lesion.
• •Patients with the following prior conditions are excluded:
• •History of chronic diarrhea, defined as more than four loose or watery stools on average daily for the past month.
• •History of grade 2 or worse peripheral neuropathy.
• •History of pancreatitis.
• •Bacterial infection requiring antibiotics within 14 days prior to study entry.
• •Prior Medication:
• •Excluded:
• •Prior HIV therapy with antiretrovirals or systemic immunomodulators.
• •Prior Treatment:
• •Excluded within 2 weeks prior to study entry:
• •Transfusion.
• •Active substance abuse or alcoholism.