A Phase I, Multicenter, Randomized Trial to Evaluate the Safety and Immunogenicity of a Recombinant Vaccinia-HIV Envelope Vaccine (HIVAC-1e) in Combination With a Panel of Subunit Recombinant HIV Envelope Vaccines

Exclusion Criteria

• •Co-existing Condition:
• •Subjects with the following symptoms or conditions are excluded:
• •Household contacts who are pregnant, \< 12 months of age, have eczema, or have immunodeficiency disease or who use immunosuppressive medications.
• •Hepatitis B surface antigenemia.
• •Medical or psychiatric condition or occupational responsibilities that preclude compliance.
• •Subjects with the following prior conditions are excluded:
• •History of immunodeficiency or chronic illness.
• •Eczema within the past year.
• •Prior Medication:
• •Excluded:
• •Prior experimental HIV vaccine.
• •Immunoglobulin administration or use of experimental agent within the past 2 months.
• •History of immunosuppressive medications.
• •Prior Treatment:
• •Excluded:
• •Blood or blood product transfusion within the previous 6 months.