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1–20 of 2,268
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SurVaxM Expanded Access Protocol
Data from clinical trials suggest that SurVaxM administered as a single agent, or in combination with standard glioblastoma chemotherapy treatment regimens to patients with…
NCT04802447
Completed
Improving Goals of Care Discussion in Advanced Cancer Patients
The goal of this study is to increase and improve Goals of Care discussions for advanced cancer patients by training medical oncologists to conduct these discussions.
NCT02374255
·
New Haven, Connecticut and 3 others
Terminated
Solriamfetol in Improving Sleep in Patients With Grade II-IV Glioma
This phase II trial studies the side effects of solriamfetol in improving sleep in patients with grade II-IV glioma. Solriamfetol is a wakefulness-promoting drug.
NCT03868943
·
Winston-Salem, North Carolina
Recruiting
Silibinin in Association With Concomitant Chemoradiotherapy and Maintenance Temozolomide in STAT3 Positive IDH Wild-type, Newly Diagnosed Glioblastoma Patients
Multicenter, double-blind, placebo-controlled, randomized trial. Patients affected by STAT3 positive newly diagnosed glioblastoma will be eligible.
NCT06964815
·
Bologna, BO and 15 others
Unknown
GX-I7 in Combination With Bevacizumab in Recurrent Glioblastoma (GBM) Patients
The purpose of this study is to evaluate the efficacy and safety of GX-I7 in combination with bevacizumab in subjects with recurrent glioblastoma.
NCT05191784
·
Seoul
Completed
Temozolomide Followed by Radiation Therapy in Treating Children With Newly Diagnosed Malignant CNS Tumors
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.
NCT00005955
·
Durham, North Carolina
Withdrawn
Effects of Steroid Tapering on Functional Capacity and Neurocognition
Purpose and Objective: 1.
NCT01169415
Active not recruiting
OKN-007 in Combination With Adjuvant Temozolomide Chemoradiotherapy for Newly Diagnosed Glioblastoma
This is a pilot study exploring the potential benefit of adding OKN-007 with Temozolomide for treatment in patients with malignant Glioblastoma undergoing adjuvant concomitant…
NCT03587038
·
Oklahoma City, Oklahoma
Active not recruiting
Lonafarnib and Temozolomide in Treating Patients with Glioblastoma Multiforme That is Recurrent or Did Not Respond to Previous Treatment with Temozolomide
This phase I trial studies the side effects and best dose of lonafarnib when given together with temozolomide and to see how well they work in treating patients with glioblastoma…
NCT00102648
·
Houston, Texas
Completed
Nativis Voyager for Newly Diagnosed GBM
This feasibility study will assess the effects of the Nativis Voyager therapy in patients newly diagnosed with GBM.
NCT03276286
·
Tucson, Arizona and 6 others
Completed
Cilengitide in Treating Younger Patients With Recurrent or Progressive High-Grade Glioma That Has Not Responded to Standard Therapy
This phase II trial studies how well cilengitide works in treating younger patients with recurrent or progressive high-grade glioma that has not responded to standard therapy.
NCT00679354
·
Oakland, California and 19 others
Completed
Radiation Therapy With or Without Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells.
NCT00006353
·
Calgary, Alberta and 15 others
Completed
Study of Sunitinib Before and During Radiotherapy in Newly Diagnosed Biopsy-only Glioblastoma Patients
Sunitinib seems to be a promising treatment for the objective of this proposal: to evaluate the clinical activity of Sunitinib as first line therapy in patients who have…
NCT01100177
·
Madrid, Madrid
Active not recruiting
LAM561 With RT and TMZ for Adults With Glioblastoma
The proposed Phase IIB/III randomized, double-blind, placebo-controlled trial in subjects with newly diagnosed primary glioblastoma multiforme (ndGBM) aims to compare the efficacy…
NCT04250922
·
Angers and 21 others
Completed
Hypofractionated Stereotactic Radiotherapy in Recurrent Glioblastoma Multiforme
Glioblastoma multiforme (GBM) is the most common primary brain tumor in adults. The treatment comprises maximal safe resection followed by radiotherapy and chemotherapy.
NCT01464177
·
São Paulo, São Paulo
Completed
Dose Evaluation Safety STudy IN Individuals With Astrocytoma Taking PolyMVA
In order to test the investigators hypothesis that 8 teaspoons of POLYMVA is safe in a population of patients with grade IV brain astrocytoma (glioblastoma multiforme), the…
NCT01833273
·
Stony Brook, New York
Completed
Metabolic Therapy Program In Conjunction With Standard Treatment For Glioblastoma
Glioblastoma (GBM), a very aggressive brain tumour, is one of the most malignant of all cancers and is associated with a poor prognosis.
NCT04730869
·
Hamilton, Waikato Region
Completed
Borderzone Sampling
On regular (diagnostic) MRI images brain tumors can show "contrast enhancement": uptake of an intravenously administered contrast agent can cause an enhancement pattern that is…
NCT00780819
·
Maastricht, Limburg
Unknown
HSRT and IMRT Chemoradiotherapy for Newly Diagnosed GBM
This study aims to evaluate the safety and effectiveness of the combination of 30Gy/5fx HSRT and 20Gy/10fx IMRT adjuvant therapy.
NCT04547621
·
Shanghai, Shanghai Municipality
Completed
Search of Protein Biomarkers in Order to Achieve a Molecular Classification of Gliomas
The aim is to classify high grade glioma by matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI MSI).
NCT02473484
·
Lille
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